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Algemene medische oncologie

Klinische studies lymfomen

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Planned

EPCORE DLBCL-4 - M22-128

A Phase 3, Open-Label, Randomized Study to Evaluate Safety and Efficacy of Epcoritamab in Combination with Gemcitabine and Oxaliplatin (GemOx) compared to Rituximab in Combination with Gemcitabine and Oxaliplatin (R-GemOx) in Subjects with Relapsed or Refractory Diffuse Large B-Cell Lymphoma

EORTC 1913LYMG (RADAR)

A randomised phase III trial with a PET response adapted design comparing ABVD +/- ISRT with A2VD +/- ISRT in patients with previously untreated stage IA/IIA Hodgkin lymphoma (RADAR)

Ongoing

GCT3013-05

A Randomized, Open-Label, Phase 3 Trial of Epcoritamab vs Investigator's Choice Chemotherapy in Relapsed/Refractory Diffuse Large B-cell Lymphoma

GCT3013-06 

A randomized, open-label, multicenter, global, phase 2 trial to evaluate the affecacy and sefety of epcoritamab as monotherapy or in comination with lenalidomide as first-line therapy for anthracycline-ineligible subjects with diffuse large B-cell lymphoma

TELLOMAK - IPH4102-201

T-cell Lymphoma Anti-KIR3DL2 Therapy. An Open Label, Multicohort, Multi-center Phase II Study Evaluating the Efficacy and Safety of IPH4102/Lacutamab Alone or in Combination With Chemotherapy in Patients With Advanced T-cell Lymphoma

Closed

COBRA EORTC-1537-LYMG

Very Early PET-response Adapted Targeted Therapy for Advanced Hodgkin Lymphoma: a Single -Arm Phase II Study

DEBIO 1562-201

A Phase 2 Study to Evaluate the Efficacy and Tolerability of Debio 1562 in Combination With Rituximab in Patients With Relapsed and/or Refractory Diffuse Large B-Cell Lymphoma and Other Forms of Non-Hodgkin's Lymphoma

MILLENNIUM C16027

An Open-Label, Rollover Protocol for Patients Previously Enrolled in Millennium-Sponsored Ixazomib Studies

PIQUR PQR309-005

Open- label, non-randomized, phase 2 study evaluating efficacy and safety of PQR309 in patients with relapsed or refractory primary CNS lymphoma

PRISM MRG106-11-203

An Open-label, Multi-Center Extension Study to Investigate the Efficacy and Safety of Cobomarsen (MRG-106) Following Systemic Treatment in Subjects With Cutaneous T-Cell Lymphoma (CTCL), Mycosis Fungoides (MF) Subtype, Who Have Completed the SOLAR Study

RESMAIN 4SC-201-6-2015

A Multicentre, Double Blind, Randomised, Placebo-controlled, Phase II Trial to Evaluate Resminostat for Maintenance Treatment of Patients With Advanced Stage (Stage IIB-IVB) Mycosis Fungoides (MF) or Sézary Syndrome (SS) That Have Achieved Disease Control With Systemic Therapy

SOLAR MRG106-11-201

A Phase 2, Randomized, Open-label, Parallel-group, Active Comparator, Multi-center Study to Investigate the Efficacy and Safety of Cobomarsen (MRG-106) in Subjects With Cutaneous T-Cell Lymphoma (CTCL), Mycosis Fungoides (MF) Subtype

TAK-981-1002

An Open Label, Dose-Escalation, Phase I Study to Evaluate the Safety, Tolerability, Preliminary Efficacy and Pharmacokinetics of TAK-981 in Adult Patients With Advanced or Metastatic Solid Tumors or Relapsed/Refractory Hematologic Malignancies

VERVOLGSTUDIE SGN35-005 of C25001 - SGN35-010

An Open-label, Treatment-option Protocol of Brentuximab Vedotin in Patients With Relapsed or Refractory Hodgkin Lymphoma, Systemic Anaplastic Large Cell Lymphoma, or CD30-positive Cutaneous T-cell Lymphoma

Laatste aanpassing: 12 maart 2024