What is a leucapheresis or white blood cell collection?
It is the collection of white blood cells using a cell separator (apheresis device). The collected cells form the basis of your cell therapy.
You will receive more information about the cell therapy from your treating doctor.
How does a white blood cell collection procedure take place?
The procedure is carried out using a cell separator, in which a centrifuge separates the different components of the blood.
- A vein is punctured in the crease of one arm. An infusion needle is inserted at this site for the blood collection. During the procedure, you may not bend this arm.
- An infusion needle is also inserted into your other arm for the return of the blood. You can usually move this arm.
- During the blood collection, an anticoagulant is used to prevent the blood from clotting in the tubes. The blood and anticoagulant flow into the centrifuge.
- In the centrifuge, the white blood cells are separated from the other blood components and directed into a collection bag. The remaining components are returned to you via the return infusion.
The collection bag containing the white blood cells is sent for further processing.
After the procedure, you will need to wait for your blood test results to be checked before you can go home.
If your veins are too narrow and blood cannot flow sufficiently through the infusion needle, the anaesthetist will insert a deep catheter (usually in the groin). This is done under local anaesthetic in the operating theatre. In this case, you will be admitted to hospital the day before the procedure (one overnight stay).
Tip
Preferably wear comfortable and practical clothing with short sleeves.
What might you experience during a white blood cell collection?
- During the procedure, a small amount of blood is in the tubing of the cell separator. This may cause some people to feel slightly dizzy or light-headed. Always inform a nurse immediately if you start to feel unwell.
- A small amount of the anticoagulant enters your bloodstream, which may cause tingling around the mouth or pins-and-needles sensations in the hands or feet. Please tell a nurse immediately if you notice any of these symptoms.
- You might feel cold, as the blood cools slightly while circulating through the machine. Don’t hesitate to ask the nurse for a blanket.
Frequently asked questions
No, you don’t need to be fasting. On the contrary, it’s better to eat something before the white blood cell collection. We also recommend drinking plenty of fluids in the days leading up to the procedure.
You may also eat and drink during the white blood cell collection. Use the arm that you’re still allowed to bend for this.
It’s a good idea to go to the toilet just before the procedure starts.
The procedure lasts an average of 3-4 hours and a maximum of 6 hours.
You should arrive between 08:00 and 08:30 Make sure to allow enough time to get to the hospital and complete your registration.
A blood test will be done first. Once the results are available, the collection can begin.
Apart from inserting the infusion needles, the procedure is painless. The arm used for the blood collection will remain stretched and may not be bent during the procedure. This can be uncomfortable.
You’ll have a personal television screen available in the day hospital. You’re also welcome to use your own laptop, smartphone, or tablet (the hospital offers free Wi-Fi), read a book or magazine, or listen to music.
If you want to watch or listen to something, please bring your own headphones or earphones. Note: Bluetooth is not supported – you’ll need a wired set with a jack plug.
Yes, you may bring someone to keep you company during the white blood cell collection. A nurse is always present in the apheresis room as well.
Most people experience no side effects during or after the procedure. However, you may feel slightly more tired afterwards. For this reason, we recommend not driving yourself home and arranging for someone to accompany you.