Klinische studies over pulmonale hypertensie

Actieve rekrutering

  • ADVANCE CAPACITY: A study evaluating the safety and effects of Ralinepag on exercise capacity assessed by cardiopulmonary exercise testing in subjects with PAH.
  • ADVANCE EXTENSION: A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension.
  • ADVANCE OUTCOMES: A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients (Ralinepag/placebo).
  • COMPERA REGISTER: Prospective registry of newly initiated therapies for pulmonary hypertension.
  • ELEVATE 2: A Study evaluating the effects of Rodatristat Ethyl in Patients with Pulmonary Arterial Hypertension.
  • EXPOSURE Register.
  • SALTO: A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension.
  • STELLAR: A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension.
  • SPHINX: A Study in Participants With Sarcoidosis-associated Pulmonary Hypertension (SAPH) to Assess the Efficacy and Safety of Oral Selexipag.
  • TORREY: (A Study to Evaluate the Efficacy and Safety of Oral Inhalation of Seralutinib for the Treatment of WHO Group 1 Pulmonary Arterial Hypertension).
  • UMBRELLA: A Clinical Study to Investigate the Long-term Safety of the Drug Macitentan in Patients With Pulmonary Hypertension Who Were Previously Treated With Macitentan in Clinical Studies.
  • UNISUS: Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension.
  • ZENITH: A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension in patients with high risk of mortality.

Toekomstige studies

  • CADENCE: A Study to Evaluate the Effects of Sotatercept versus Placebo for the Treatment of Combined Postcapillary and Precapillary Pulmonary Hypertension due to Heart Failure with Preserved Ejection Fraction.
  • HYPERION: Study to Evaluate Sotatercept When Added to Background Pulmonary Arterial Hypertension Therapy in Newly Diagnosed Intermediate- and High-risk PAH Patients.
  • IMPAHCT: A Dose Ranging and Confirmatory Study to Evaluate the Safety and Efficacy of AV-101 in Patients with Pulmonary Arterial Hypertension.
  • INSIGNIA: Study to Evaluate the Efficacy and Safety of MK-5475 in Adults with Pulmonary Arterial Hypertension.
  • INS1009-202: Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Treprostinil Palmitil Inhalation Powder in Participants with Pulmonary Arterial Hypertension.
  • INS1009-211: Study to Evaluate the Safety and Tolerability of Treprostinil Palmitil Inhalation Powder in Participants with Pulmonary Hypertension Associated with Interstitial Lung Disease.
  • PAH CARE REGISTER.
  • PLATYPUS: A Prospective, Open-label, Platform Study for Long-term Follow-up of Participants Using Study Intervention in Pulmonary Hypertension Parent Studies.
  • SOTERIA: An Open-Label Long-term Follow-up Study to Evaluate the Effects of Sotatercept When Added to Background Pulmonary Arterial Hypertension Therapy for the Treatment of PAH.

Contact

Centrum pulmonale hypertensie
Laatste aanpassing: 14 juni 2022